Immunotherapy has shifted the therapeutic landscape in thoracic cancers.However, assessment of biomarkers for patient selection and disease monitoring remain challenging, especially considering the lack of tissue DisplayPort to HDMI Type A sample availability for clinical and research purposes.In this scenario, liquid biopsy (LB), defined as the st
ALOX5 is implicated in chronic myeloid leukemia development in mouse leukemic Electronic Hood Lock stem cells, but its importance in human chronic myeloid leukemia is unknown.Functional ALOX5 was assessed using an LTB4 ELISA and ALOX5, and LTB4R1 mRNA expression was determined via a TaqMan gene expression assay.LTB4R1 and 5-LOX protein levels were
Abstract Background The UK Clinical Research Collaboration (UKCRC) registered Clinical Trials Units (CTUs) Network aims to support high-quality, efficient and sustainable clinical trials research in the UK.To better understand the challenges in efficient trial conduct, and to help prioritise tackling these challenges, we surveyed CTU staff.The aim
HIV-1 protease gene sequences were obtained from peripheral blood, saliva or oral tissues of 35 HIV+ patients using nested amplification and manual sequencing of PCR products.Of the 35 HIV+ patients 9 had clinical oropharyngeal candidiasis (OPC) while 26 did not, and only 4 patients were on protease inhibitor (PI) therapy.These patients were collec